ESV Reformation Study Bible – Rom 1:3–4
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Rom 1:3–4

1:3, 4 A description of the two stages of the Savior’s ministry, rather than of His two natures. Although Son of God, He was “descended from David” in order to share our weakness, but was transformed by the “Spirit of holiness” at the Resurrection, and was brought into a new epoch of His personal human existence (1 Cor. 15:45; 2 Cor. 13:4).